West Ham United will travel to Manchester United for their Emirates FA Cup fifth round tie on Tuesday 9 February.
The Old Trafford clash will kick-off at 7.30pm, broadcast live in the UK on BBC One and BBC iPlayer.
David Moyes' men have seen off Stockport County and Doncaster Rovers to reach the last 16 stage of the competition, while the Red Devils overcame the challenge of Liverpool in round four, having defeated Watford in the third round.
West Ham and Manchester United have been drawn together on nine previous occasions in the FA Cup, with the Hammers progressing on four of those, including famously at Old Trafford in 2001, when Paolo Di Canio scored the only goal of the game.