Collins played his part in a memorable 3-0 victory over Crystal Palace in the last home game and will never forget how the Hammers fans played their part in helping the Club secure all three points.
The Wales international has no doubts it was the best atmosphere that has been generated at London Stadium this season and hopes to see the same level of support against Manchester City.
Following the disappointing defeat against Pep Guardiola's side in the Emirates FA Cup Third Round at the start of January, Collins says the players are determined to make amends and feels the home support can play a significant role.
Collins said: “The fans were our 12th man and it was one of the best atmospheres I have seen at London Stadium (against Palace).
“It was incredible and they knew we all had to pull together in what was a difficult week. Everyone stuck together and we managed to get the win.
“It is massive when we have all our fans behind us. You go to places like Old Trafford and Anfield and all their fans are shouting for them and it makes a hell of a difference.
“The fans are on you every time you make a little mistake or a bad pass. To have that in our favour at home where we have not played as well as what we would have liked, makes a big difference.
“To see all the fans happy and for everything to click together made it even more special. Hopefully every game can be like that.
“I can see London Stadium becoming a fortress if we continue to play like that. A lot has been made about the Stadium and it has been different. It takes getting used to for everyone, but we hope that is how it can be every week.”