Gary O'Neil is set to be at the Stadium Superstore on Monday afternoon to help promote a Stroke Association awareness campaign.
The Hammers midfielder will be meeting stroke survivor Andy Jones, who is visiting every single Premier League football ground in the space of five days.
O'Neil will also be meeting fans instore and signing autographs from around 2.30pm.
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The main aim of the event will be to promote the Stroke Awareness campaign.
Andy, 47, had a stroke in December 2003 that was caused by high blood pressure. He was initially left with no speech and paralysis down one side of his body. Yet after a week in hospital and an even longer period of recovery back at home, Andy's dedication and courage paid off when he was able to return to full-time employment.
He now works as a stroke coordinator in helping fellow stroke survivors get their lives back on track following their stroke.
He said: "We all get very emotional and stressed whilst watching football which has an impact on your blood pressure. This is particularly the case if you live an unhealthy lifestyle without much exercise and poor diet.
Kate Allan, Know Your Blood Pressure Co-ordinator at the Stroke Association, said: "Andy's challenge is a brilliant light-hearted way of communicating a very serious message.
"Our research has found that around 40 per cent of men and 30 per cent of women have high blood pressure and the majority of them are not receiving treatment or even aware of it.
"One of the biggest challenges is to make people understand that strokes don't just happen to older people. They can happen to anyone, at any age. The blood pressure test is short, painless and simple and so we urge people to get tested".
The Know Your Blood Pressure Premier League Challenge is designed to target the aforementioned sector of the population and encourage them to visit www.stroke.org.uk/plchallenge to find out where their nearest Know Your Blood Pressure event is taking place.
The Know Your Blood Pressure Premier League Challenge will take place from 11 to 15 April, kicking off at Arsenal's Emirates Stadium and ending at Sunderland's Stadium of Light.
*Please note all appearances are subject to change for footballing reasons. All fans attending are advised to check whufc.com for the latest information.