West Ham United will take on Everton away should they get beyond Middlesbrough in Tuesday week's FA Cup fifth-round replay.
The potential tie would be the first FA Cup meeting between the clubs since the memorable 11 March 1991 sixth-round tie at the Boleyn Ground when goals from Stuart Slater and Colin Foster ensured a 2-1 win and took the Hammers through to the semi-finals. Once there, John Lyall's ten men - after the harsh dismissal of Tony Gale - lost out 4-0 to Nottingham Forest.
In more recent action, Everton won 3-1 in east London back on 8 November with the return Barclays Premier League encounter still to come at Goodison Park on 16 May. Last season, the Toffees also travelled to east London for a League Cup quarter-final, winning 2-1 before coming unstuck in the last four.
The FA Cup sixth-round draw took place on Sunday evening with Frank McLintock and Graeme Souness conducting proceedings from FA headquarters in Soho Square, London. The ties will be staged on the weekend of 7/8 March.
West Ham United made sure of a place in the draw after Saturday's 1-1 home draw with Middlesbrough, having beaten Barnsley and Hartlepool United in the previous two rounds. Everton won through with a 3-1 home defeat of Aston Villa on Sunday afternoon, having previously disposed of Macclesfield Town and Liverpool. They have not been in the quarter-finals since the 2001/02 season.
Fifth-round draw
Blackburn Rovers or Coventry City v Chelsea
Swansea City or Fulham v Manchester United
Cardiff City or Arsenal or Burnley v Sheffield United or Hull City
Everton v Middlesbrough or West Ham United